Nitroglycerine, not digoxin, is an example of a cardiac medication that is used primarily for the effect of vasodilation of the coronary arteries
This is not a complete list of side effects and others may occur
, The signs and symptoms of congestive heart failure are related to the backup of blood in the vascular system and the loss of fluid to the tissues
However, in these patients an association between digoxin use and high risk of sudden cardiac death was observed (HR 1
Digoxin increases myocardial contractility in pediatric patients with congestive heart failure
The effect of digoxin upon the electrical activity of the heart is complex and consists of a number of direct and indirect A patient is receiving digoxin (Lanoxin) for the treatment of heart failure
This leads to increased cardiac contractility and cardiac output, characteristics that are central to digoxin-mediated treatment of heart failure
This review reconsiders the historical and contemporary interpretations of the terms cardiac performance and inotropy and recommends a modern definition of myocardial contractility as the preload, afterload and length-independent intrinsic kinetically controlled, chemo-mechanical processes responsible for the development of
Binding with the sodium pump increases intracellular Na+ concentration, which will drive Ca2+ influx
CNS, decreased myocardial contractility, arrhythmia: Phenytoin: 2-5 mg/kg IV over 5-10 min, repeat up to 20 mg/kg: 2-8 mg/kg q 8-12 hrs P